• The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9 

      Bayly-Jones, Charles; Ho, Bill H. T.; Lau, Corinna; Leung, Eleanor W. W.; D’Andrea, Laura; Lupton, Christopher J.; Ekkel, Susan M.; Venugopal, Hariprasad; Whisstock, James C.; Mollnes, Tom Eirik; Spicer, Bradley A.; Dunstone, Michelle A. (Peer reviewed; Journal article, 2023)
      The Membrane Attack Complex (MAC) is responsible for forming large β-barrel channels in the membranes of pathogens, such as gram-negative bacteria. Off-target MAC assembly on endogenous tissue is associated with inflammatory ...